Melola Discovery

← Melola Discovery

Open access Jurnal

Uji Toksisitas Akut Ekstrak dan Fraksi Kulit Batang Ketapang Laut (Terminalia Catappa L.) Menggunakan Metode BSLT

Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan · Vol. 6 No. 1 (2020) · pp. 42–47

DOI
10.33772/pharmauho.v6i1.11430
ISSN
2715-4181
Published
2020-04-22
Publisher
Fakultas Farmasi Universitas Halu Oleo
Language
eng
License
creativecommons.org/licenses/by-sa/4.0

Abstract

AbstrakToksisitas akut merupakan kemampuan suatu bahan kimia (obat/bahan obat) dalam menimbulkan kerusakan pada suatu organisme dalam waktu yang relatif singkat. Tujuan penelitian ini adalah untuk mengetahui potensi ketoksikan akut dari ekstrak metanol, fraksi etil asetat dan fraksi air kulit batang ketapang laut (Terminalia catappa L.). Pengujian toksisitas akut dilakukan dengan menggunakan metode BSLT (Brine Shrimp Lethality Test) dan menggunakan analisis program untuk mengetahui nilai LC50 dari ekstrak dan fraksi. Hasil uji toksisitas akut menunjukan nilai LC50 dari ekstrak metanol, fraksi etil asetat dan fraksi air kulit batang ketapang laut (Terminalia catappa L. ) berturut-turut 247,997 ppm; 400,666 ppm dan 618,046 ppm. Hal ini menunjukan bahwa ekstrak metanol batang ketapang laut (Terminalia catappa L.) bersifat paling toksik dibandingkan fraksi etil asetat dan fraksi air.Kata kunci: Ekstrak, Fraksi, Terminalia catappa L., BSLT, Artemia salina LeachAbstractAcute toxicity is the ability of chemical (drug/drug ingredient) to cause damage to organisms in a relatively short time. The purpose of this study was to determine the potential for acute toxicity of methanol extract, ethyl acetate and water fractions of sea ketapang stem skin (Terminalia catappa L.). Acute toxicity testing was performed using the BSLT (Brine Shrimp Lethality Test) method and program analysis to determine the LC50 values of extracts and fractions. The results of the acute toxicity test showed the LC50 values of methanol extract, ethyl acetate and water fractions of the plant stem skin consecutively were 247,997 ppm; 400,666 ppm and 618,046 ppm. This shows that the methanol extract of sea ketapang stems (Terminalia catappa L.) is the most toxic compared to the ethyl acetate and the water fraction.Keywords: Extract, Fraction, Terminalia catappa L., BSLT, Artemia salina Leach

Keywords

Collaboration network of the authors

40 authors · 159 co-authorship links · 2 across different organisations · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Universitas Halu Oleo
  • Institut Teknologi dan Kesehatan Avicenna
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Rini HamsidiAffiliation unknown4
S SabarudinAffiliation unknown4
Nur Fitriana Muhammad AliInstitut Teknologi dan Kesehatan Avicenna3
Suryani SuryaniUniversitas Halu Oleo3
Wa Ode Sitti ZubaydahUniversitas Halu Oleo2
Ruslin RuslinUniversitas Halu Oleo2
Kobajashi Togo IsamuAffiliation unknown2
La Ode Muhammad FitrawanUniversitas Halu Oleo2
Sania HairahAffiliation unknown2
Syahlan HermanAffiliation unknown2
R RuslinAffiliation unknown2
W WahyuniAffiliation unknown2
Muhammad Hajrul MalakaAffiliation unknown2
Fery Indradewi ArmadanyAffiliation unknown2
Henny KasmawatiUniversitas Halu Oleo2
Halimahtussaddiyah RitongaAffiliation unknown2
Dian Munasari SoloUniversitas Halu Oleo1
Ardiyanti ArdiyantiAffiliation unknown1
Nurhayani HMAffiliation unknown1
Muhammad Juharisman SaputraAffiliation unknown1
Wa BaaneAffiliation unknown1
S SahidinAffiliation unknown1
Mesi LeoritaAffiliation unknown1
Sandra Aulia MardikasariAffiliation unknown1
Wahyuni WahyuniAffiliation unknown1
Rifa'atul MahmudahAffiliation unknown1
H HalikAffiliation unknown1
R RamlahAffiliation unknown1
Linda PriartiAffiliation unknown1
Andi Nafisah Tendri Adjeng MallarangengAffiliation unknown1
Husnaeni HusnaeniAffiliation unknown1
Aty WidyawaruyantiAffiliation unknown1
Achmad Fuad HafidAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/pharmauho/oai, first harvested 30 Okt 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Uji Toksisitas Akut Ekstrak dan Fraksi Kulit Batang Ketapang Laut (Terminalia Catappa L.) Menggunakan Metode BSLT</dc:title>
	<dc:creator>Sartinah, Ari</dc:creator>
	<dc:creator>Yamin, Y</dc:creator>
	<dc:creator>Arba, Muhammad</dc:creator>
	<dc:creator>Akib, Nur Illiyyin</dc:creator>
	<dc:creator>Adjeng, Andi Nafisah Tendri</dc:creator>
	<dc:creator>Nurhasana, N</dc:creator>
	<dc:creator>Pascayantri, Asniar</dc:creator>
	<dc:subject xml:lang="en-US">Extract, Fraction, Terminalia catappa L., BSLT, Artemia salina Leach</dc:subject>
	<dc:description xml:lang="en-US">AbstrakToksisitas akut merupakan kemampuan suatu bahan kimia (obat/bahan obat) dalam menimbulkan kerusakan  pada suatu organisme dalam waktu yang relatif singkat. Tujuan penelitian ini adalah untuk mengetahui potensi ketoksikan akut dari ekstrak metanol, fraksi etil asetat dan fraksi air kulit batang ketapang laut (Terminalia catappa L.). Pengujian toksisitas akut dilakukan dengan menggunakan metode BSLT (Brine Shrimp Lethality Test) dan menggunakan analisis program untuk mengetahui nilai LC50 dari ekstrak dan fraksi. Hasil uji toksisitas akut menunjukan nilai LC50  dari ekstrak metanol, fraksi etil asetat dan fraksi air kulit batang ketapang laut (Terminalia catappa L. )  berturut-turut 247,997 ppm; 400,666 ppm dan 618,046 ppm. Hal ini menunjukan bahwa ekstrak metanol batang ketapang laut (Terminalia catappa L.) bersifat paling toksik dibandingkan fraksi etil asetat dan fraksi air.Kata kunci: Ekstrak, Fraksi, Terminalia catappa L., BSLT, Artemia salina LeachAbstractAcute toxicity is the ability of chemical (drug/drug ingredient) to cause damage to organisms in a relatively short time. The purpose of this study was to determine the potential for acute toxicity of methanol extract, ethyl acetate and water fractions of sea ketapang stem skin (Terminalia catappa L.). Acute toxicity testing was performed using the BSLT (Brine Shrimp Lethality Test) method and program analysis to determine the LC50 values of extracts and fractions. The results of the acute toxicity test showed the LC50 values of methanol extract, ethyl acetate and water fractions of the plant stem skin consecutively were 247,997 ppm; 400,666 ppm and 618,046 ppm. This shows that the methanol extract of sea ketapang stems (Terminalia catappa L.) is the most toxic compared to the ethyl acetate and the water fraction.Keywords: Extract, Fraction, Terminalia catappa L., BSLT, Artemia salina Leach</dc:description>
	<dc:publisher xml:lang="en-US">Fakultas Farmasi Universitas Halu Oleo</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2020-04-22</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US"></dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ojs.uho.ac.id/index.php/pharmauho/article/view/11430</dc:identifier>
	<dc:identifier>10.33772/pharmauho.v6i1.11430</dc:identifier>
	<dc:source xml:lang="en-US">Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan; Vol 6, No 1 (2020): Pharmauho; 42-47</dc:source>
	<dc:source>2715-4181</dc:source>
	<dc:source>10.33772/pharmauho.v6i1</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/pharmauho/article/view/11430/8751</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2020 Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan</dc:rights>
	<dc:rights xml:lang="en-US">http://creativecommons.org/licenses/by-sa/4.0</dc:rights>
</oai_dc:dc>