Melola Discovery

← Melola Discovery

Open access Jurnal

Effect of Stromal Vascular Fraction and Platelet-Rich Plasma Combination on Polymorphonuclear Cells in Wistar Rats Anal Trauma Model

Nusantara Medical Science Journal · Vol. ume (2022) · pp. 119–128

DOI
10.20956/nmsj.v7i2.20846
ISSN
2597-7288, 2460-9757
Published
2022-10-21
Publisher
Faculty of Medicine, Hasanuddin University.
Language
en
License
creativecommons.org/licenses/by/4.0

Abstract

Introduction: By relying on polymorphonuclear (PMN) cells, stromal vascular fraction (SVF) and platelet-rich plasma (PRP) contribute significantly in the healing process. Through anal trauma model, this study examined the effect of SVF and PRP combination on PMN counts in vivo. Method: Three groups of twenty-eight eligible Wistar rats anal trauma model randomly assigned to receive SVF and PRP combination (Group A), normal saline (Group B), or healthy controls (Group C). On days 1, 7, and 14, we examined at PMN cell counts in Groups A and B. Group C were sacrificed early to acquire baseline data on PMN cells. Results: On the first day, Group A had more PMN cells than Group B, but this difference faded by days 7 and 14. On day 1, the test revealed a significant increase in PMN cells (p=0.002). Conclusion: Combining SVF and PRP can improve PMN cells' acute phase of anal damage repair in vivo

Collaboration network of the authors

34 authors · 115 co-authorship links

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Punggawa Gauk KarimAffiliation unknown1
Hafsah KatuAffiliation unknown1
Irfan SugiantoAffiliation unknown1
Andi Abidah RustamAffiliation unknown1
Andi IhwanAffiliation unknown1
Kenny Edward YapAffiliation unknown1
Andi Asadul IslamAffiliation unknown1
Junus Asiu Bulu BaanAffiliation unknown1
Rizalinda SjahrilAffiliation unknown1
Wahyunita Do TokaAffiliation unknown1
Zainab AzisAffiliation unknown1
M. Husni CangaraAffiliation unknown1
Andi Alfian ZainuddinAffiliation unknown1
Syarifuddin WahidAffiliation unknown1
Upik A. MiskadAffiliation unknown1
Nur Indah PurnamasariAffiliation unknown1
Muhammad SabirAffiliation unknown1
SRI WAHYUNIAffiliation unknown1
Burhanuddin BaharAffiliation unknown1
Rosdiana NatzirAffiliation unknown1
Mochammad HattaAffiliation unknown1
Ahyar AhmadAffiliation unknown1
Ade Rifka JunitaAffiliation unknown1
Ressy DwiyantiAffiliation unknown1
Muhammad Reza PrimagunaAffiliation unknown1
Muhammad Nasrum MassiAffiliation unknown1
Rosana AgusAffiliation unknown1
Raymond TumandukAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/jmednus/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Effect of Stromal Vascular Fraction and Platelet-Rich Plasma Combination on Polymorphonuclear Cells in Wistar Rats Anal Trauma Model</dc:title>
	<dc:creator xml:lang="en">Chandra, Erwin</dc:creator>
	<dc:creator xml:lang="en">Sulmiati, Sulmiati</dc:creator>
	<dc:creator xml:lang="en">Mariana, Nita</dc:creator>
	<dc:creator xml:lang="en">Josh, Fonny</dc:creator>
	<dc:creator xml:lang="en">Rachman, Sachraswaty</dc:creator>
	<dc:creator xml:lang="en">Hamid, Firdaus</dc:creator>
	<dc:description xml:lang="en">Introduction: By relying on polymorphonuclear (PMN) cells, stromal vascular fraction (SVF) and platelet-rich plasma (PRP) contribute significantly in the healing process. Through anal trauma model, this study examined the effect of SVF and PRP combination on PMN counts in vivo. Method: Three groups of twenty-eight eligible Wistar rats anal trauma model randomly assigned to receive SVF and PRP combination (Group A), normal saline (Group B), or healthy controls (Group C). On days 1, 7, and 14, we examined at PMN cell counts in Groups A and B. Group C were sacrificed early to acquire baseline data on PMN cells. Results:  On the first day, Group A had more PMN cells than Group B, but this difference faded by days 7 and 14. On day 1, the test revealed a significant increase in PMN cells (p=0.002). Conclusion:  Combining SVF and PRP can improve PMN cells' acute phase of anal damage repair in vivo</dc:description>
	<dc:publisher xml:lang="en">Faculty of Medicine, Hasanuddin University.</dc:publisher>
	<dc:date>2022-10-21</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/jmednus/article/view/20846</dc:identifier>
	<dc:identifier>10.20956/nmsj.v7i2.20846</dc:identifier>
	<dc:source xml:lang="en">Nusantara Medical Science Journal; Volume 7 Issue 2, July - December 2022; 119-128</dc:source>
	<dc:source>2597-7288</dc:source>
	<dc:source>2460-9757</dc:source>
	<dc:source>10.20956/nmsj.v7i2</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/jmednus/article/view/20846/8761</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2022 Nusantara Medical Science Journal</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>