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Microencapsulation by Spray drying of Cosmos caudatus Kunth. Extracts Using Gum Arabic: Influencing Factors and Controlled Release

Indonesian Food Science and Technology Journal · Vol. 8 No. 1 (2024) · hlm. 27–35

DOI
10.22437/ifstj.v8i1.32818
ISSN
2615-367X
Terbit
2024-12-28
Penerbit
Department of Technology of Agricultural product (THP) Jambi University
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Advanced drug delivery systems are required due to the increasing advancement in science and technology, with a common example being microencapsulation. This system is affected by the manufacturing conditions and slow release of bioactive compounds inside microcapsule. In general, phytochemicals in the edible plant, Cosmos caudatus Kunth, specifically flavonoids, offer several health benefits but are susceptible to degradation which reduces biological activities. Therefore, this study aimed to encapsulate extract using spray drying method, which can be used as wall material in Gum Arabic. Microencapsulated product was also tested for biological activities. The effect of microcapsule production was investigated, including the concentration of wall material and the stirring speed. Furthermore, the optimal conditions of microcapsule were selected based on the highest encapsulation efficiency. The results showed that a concentration of 4% (w/v) Gum Arabic and a stirring speed of 800 rpm were the optimal conditions, leading to a percentage release of 71.87%. Microcapsule under these conditions produced an IC50 value of 55.09 ± 0.57 ug/mL as an inhibitor of alpha-amylase enzyme. The characterization by scanning electron microscope (SEM) showed spherical forms with a mean diameter of 152.00 um. The bioactive substance in microcapsule was released at pH 2.2 and pH 7.4 for 30 to 120 min, with a percentage release of 38.05% and 95.14%, respectively. In conclusion, this study confirmed that microencapsulation played a crucial role in the development of plant extract with retained biological functions.

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  • Sekolah Tinggi Agama Buddha Negeri Raden Wijaya Wonogiri
  • Universitas Hang Tuah
  • University of Brawijaya
  • Universitas Jambi
  • Universitas Muslim Indonesia
  • Universitas PGRI Semarang
  • Universitas Halu Oleo
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Robert TambunAfiliasi tidak diketahui2
Hadi PrasutiyonAfiliasi tidak diketahui2
Robert TambunUniversitas Hang Tuah2
Hadi PrasutiyonUniversitas Hang Tuah2
Hima Sakina FirdhausyAfiliasi tidak diketahui2
Fatmawati - FatmawatiAfiliasi tidak diketahui2
Restina BemisUniversitas Jambi2
Heriyanti HeriyantiAfiliasi tidak diketahui2
Samsidar SamsidarUniversitas Muslim Indonesia2
Indra Lasmana TariganAfiliasi tidak diketahui2
Madyawati LatiefAfiliasi tidak diketahui2
TEZZA ADRIANSYAH ANWARAfiliasi tidak diketahui2
Dian Eka RatnawatiUniversity of Brawijaya1
Rozaq AkbarUniversity of Brawijaya1
Bagus PanuntunAfiliasi tidak diketahui1
Fikri Irfan AdristiAfiliasi tidak diketahui1
Sutrisno SutrisnoUniversitas Hang Tuah1
Sutrisno SutrisnoUniversitas PGRI Semarang1
Lery PrasetyoSekolah Tinggi Agama Buddha Negeri Raden Wijaya Wonogiri1
Metta Puspita DewiSekolah Tinggi Agama Buddha Negeri Raden Wijaya Wonogiri1
Dwi PurwantiAfiliasi tidak diketahui1
Dwi HaryadiAfiliasi tidak diketahui1
Jeanne Darc Noviayanti ManikAfiliasi tidak diketahui1
Sunarto .Afiliasi tidak diketahui1
Ambiro Puji AsmaroiniAfiliasi tidak diketahui1
Della Futvy SekarningrumAfiliasi tidak diketahui1
Syahdara Anisa MakrufAfiliasi tidak diketahui1
Zalik NuryanaAfiliasi tidak diketahui1
Sutomo SutomoAfiliasi tidak diketahui1
Aries MusnandarAfiliasi tidak diketahui1
Diaya Uddeen Deab Mahmoud AlzitawiAfiliasi tidak diketahui1
Ahmad SajidinAfiliasi tidak diketahui1
Abdul KadirUniversitas Halu Oleo1
Froilan Delute MoboAfiliasi tidak diketahui1
Galih Wisnu WardhanaAfiliasi tidak diketahui1
Hozana AuliaAfiliasi tidak diketahui1

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Sumber metadata: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/ifstj/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Microencapsulation by Spray drying of Cosmos caudatus Kunth. Extracts Using Gum Arabic: Influencing Factors and Controlled Release</dc:title>
	<dc:creator xml:lang="en">Zahara, Izaz Aqeiluz</dc:creator>
	<dc:creator xml:lang="en">Sutrisno, Sutrisno</dc:creator>
	<dc:creator xml:lang="en">Ulfa, Siti Mariyah</dc:creator>
	<dc:creator xml:lang="en">Safitri, Anna</dc:creator>
	<dc:subject xml:lang="en">Cosmos caudatus Kunth</dc:subject>
	<dc:subject xml:lang="en">gum Arabic</dc:subject>
	<dc:subject xml:lang="en">microencapsulation</dc:subject>
	<dc:subject xml:lang="en">SEM</dc:subject>
	<dc:subject xml:lang="en">release</dc:subject>
	<dc:description xml:lang="en">Advanced drug delivery systems are required due to the increasing advancement in science and technology, with a common example being microencapsulation. This system is affected by the manufacturing conditions and slow release of bioactive compounds inside microcapsule. In general, phytochemicals in the edible plant, Cosmos caudatus Kunth, specifically flavonoids, offer several health benefits but are susceptible to degradation which reduces biological activities. Therefore, this study aimed to encapsulate extract using spray drying method, which can be used as wall material in Gum Arabic. Microencapsulated product was also tested for biological activities. The effect of microcapsule production was investigated, including the concentration of wall material and the stirring speed. Furthermore, the optimal conditions of microcapsule were selected based on the highest encapsulation efficiency. The results showed that a concentration of 4% (w/v) Gum Arabic and a stirring speed of 800 rpm were the optimal conditions, leading to a percentage release of 71.87%. Microcapsule under these conditions produced an IC50 value of 55.09 ± 0.57 ug/mL as an inhibitor of alpha-amylase enzyme. The characterization by scanning electron microscope (SEM) showed spherical forms with a mean diameter of 152.00 um. The bioactive substance in microcapsule was released at pH 2.2 and pH 7.4 for 30 to 120 min, with a percentage release of 38.05% and 95.14%, respectively. In conclusion, this study confirmed that microencapsulation played a crucial role in the development of plant extract with retained biological functions.</dc:description>
	<dc:publisher xml:lang="en">Department of Technology of Agricultural product (THP) Jambi University</dc:publisher>
	<dc:date>2024-12-28</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/ifstj/article/view/32818</dc:identifier>
	<dc:identifier>10.22437/ifstj.v8i1.32818</dc:identifier>
	<dc:source xml:lang="en">Indonesian Food Science and Technology Journal; Vol. 8 No. 1 (2024): Volume 8 Number 1, December 2024 |IFSTJ| ; 27-35</dc:source>
	<dc:source>2615-367X</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/ifstj/article/view/32818/19671</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Indonesian Food Science and Technology Journal</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>