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Effect of Acid-Base Composition on Physical Characteristicsand Antioxidant Activity of “Beras Kencur” EffervescentTablet

Sainteknol : Jurnal Sains dan Teknologi · Vol. 22 No. 2 (2024) · pp. 73–79

DOI
10.15294/sainteknol.v22i2.20080
ISSN
2527-3604, 0216-4566
Published
2024-12-31
Publisher
Universitas Negeri Semarang
Language
eng

Abstract

This study aimed to evaluate the effect of acid-base ratio on the physical characteristics and antioxidant activity of the beras kencur effervescent tablet formulation. The formulation determination was based on the percentage inhibition value, where the highest value (76.2%) was found in beras kencur at 10 mg/mL, so that 1.5 g is needed to achieve the highest potential of radical scavenging activity. In this case, 1.5 g of sample was then incorporated into three effervescent tablets. The acid-to-base ratios used in this study were 1: 1.25 (F1), 1: 1.50 (F2), and 1: 2.50 (F3). The tablets were evaluated for pH, dissolution time, total phenolic content (TPC), and antioxidant activity. The results showed that a higher proportion of base (F3) improved solubility. Meanwhile, antioxidant activity evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) test, and total phenolic content determined using Folin-Ciocalteau, showed that tablets with a higher proportion of acid exhibited higher total phenolic content. However, considering that all three samples have very strong antioxidant activity, it can be concluded that F3 is the optimal formulation.

Collaboration network of the authors

40 authors · 159 co-authorship links · showing the 40 most connected

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  • State University of Semarang
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Ella KusumastutiAffiliation unknown8
Jumaeri JumaeriAffiliation unknown4
Catur Rini WidyastutiAffiliation unknown4
Endang SusilaningsihState University of Semarang3
Rini JulistiaAffiliation unknown3
Agung Tri PrasetyaState University of Semarang2
Dwi IramadhaniAffiliation unknown2
Zurratul MunaAffiliation unknown2
Ratna Dewi KusumaningtyasAffiliation unknown2
Zuhriyan Ash Shiddieqy BahlawanAffiliation unknown2
Nuril HudaAffiliation unknown1
Siti Herlina DewiState University of Semarang1
SRI WAHYUNIAffiliation unknown1
Mohammad Haris BaihaqiAffiliation unknown1
Fika Maulydha HardiyantiAffiliation unknown1
Eka Siti RinjaniAffiliation unknown1
Moch Faizal RachmadiAffiliation unknown1
Haniif PrasetiawanAffiliation unknown1
Nadya Alfa Cahaya ImaniAffiliation unknown1
Rizky IchwanAffiliation unknown1
Syifa Azzahra Putri S.Affiliation unknown1
Masrukan MasrukanState University of Semarang1
Ani RusilowatiState University of Semarang1
Heru SetyantoAffiliation unknown1
Tri Sri NoorAsihAffiliation unknown1
R SusantiAffiliation unknown1
Woro SumarniState University of Semarang1
Fatimah KhoirunisaAffiliation unknown1
Sri Susilogati SumartiState University of Semarang1
Nanik WijayatiState University of Semarang1
Inca Pritonasya MilaningsihAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/journals/sainteknol/oai, first harvested 6 Nov 2026, last seen 6 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Effect of Acid-Base Composition on Physical Characteristicsand Antioxidant Activity of “Beras Kencur” EffervescentTablet</dc:title>
	<dc:creator xml:lang="en">Astuti, Widi </dc:creator>
	<dc:creator xml:lang="en">Putri, Radenrara Dewi Artanti </dc:creator>
	<dc:creator xml:lang="en">Sulistyaningsih, Triastuti </dc:creator>
	<dc:creator xml:lang="en">Azany, Ghaefira Tasya  </dc:creator>
	<dc:creator xml:lang="en">Alexandra, Natasya Viona </dc:creator>
	<dc:creator xml:lang="en">Saputri, Ria </dc:creator>
	<dc:creator xml:lang="en">Jannah, Reni Ainun </dc:creator>
	<dc:creator xml:lang="en">Hadikawuryan, Danang Subarkah  </dc:creator>
	<dc:creator xml:lang="en">Fitri, Zulfa Ajrina </dc:creator>
	<dc:description xml:lang="en">This study aimed to evaluate the effect of acid-base ratio on the physical characteristics and antioxidant activity of the beras kencur effervescent tablet formulation. The formulation determination was based on the percentage inhibition value, where the highest value (76.2%) was found in beras kencur at 10 mg/mL, so that 1.5 g is needed to achieve the highest potential of radical scavenging activity. In this case, 1.5 g of sample was then incorporated into three effervescent tablets. The acid-to-base ratios used in this study were 1: 1.25 (F1), 1: 1.50 (F2), and 1: 2.50 (F3). The tablets were evaluated for pH, dissolution time, total phenolic content (TPC), and antioxidant activity. The results showed that a higher proportion of base (F3) improved solubility. Meanwhile, antioxidant activity evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) test, and total phenolic content determined using Folin-Ciocalteau, showed that tablets with a higher proportion of acid exhibited higher total phenolic content. However, considering that all three samples have very strong antioxidant activity, it can be concluded that F3 is the optimal formulation.</dc:description>
	<dc:publisher xml:lang="en">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2024-12-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/journals/sainteknol/article/view/20080</dc:identifier>
	<dc:identifier>10.15294/sainteknol.v22i2.20080</dc:identifier>
	<dc:source xml:lang="en">Sainteknol : Jurnal Sains dan Teknologi; Vol. 22 No. 2 (2024): December 2024; 73-79</dc:source>
	<dc:source>2527-3604</dc:source>
	<dc:source>0216-4566</dc:source>
	<dc:source>10.15294/sainteknol.v22i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/journals/sainteknol/article/view/20080/2818</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Sainteknol : Jurnal Sains dan Teknologi</dc:rights>
</oai_dc:dc>