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IN VITRO PHARMACOLOGICAL ACTIVITY TEST OF TELANG FLOWER KOMBUCHA AS ANTIBACTERIAL Vibrio Cholerae AND Shigella dysenteriae THROUGH FERMENTATION BIOTECHNOLOGY METHOD

BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan · Vol. 11 No. 2 (2025) · pp. 130–146

DOI
10.22373/biotik.v11i2.17427
ISSN
2549-1768, 2337-9812
Published
2025-09-23
Publisher
Universitas Islam Negeri Ar-Raniry
Language
eng
License
creativecommons.org/licenses/by-sa/4.0

Abstract

Diarrhea that occurs in the digestive tract is a big problem for human intestinal health. This can be caused by the activity of pathogenic bacteria in the form of Vibrio cholera and Shigella dysinteriae. In this study, kombucha has been shown to have pharmacological activity in vitro in inhibiting the growth of Vibrio cholera and Shigella dysinteriae bacteria at all sugar concentrations. The purpose of this study was to determine the in vitro pharmacological activity of the butterfly pea flower kombucha in inhibiting the growth of the two test bacteria consisting of a sugar concentration of 20%, 30% and 40%. The method for testing the inhibition of both bacterial growth tests is disc diffusion. One way ANOVA and post hoc analysis are one of the quantitative test methods used in this study of the average diameter of the inhibition zone of teal flower kombucha from various sugar concentrations. The results of this study have proven based on a one-way ANOVA with each P value> 0.05 and then continued through post hoc analysis concluded that the telang flower kombucha at a concentration of 40% is the best treatment in inhibiting the growth of both test bacteria where the concentration is significantly different from sugar concentration 20% and 30%.

Keywords

Collaboration network of the authors

40 authors · 117 co-authorship links · showing the 40 most connected

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  • Universitas Halu Oleo
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Hari HariadiAffiliation unknown4
Muhammad AndryAffiliation unknown3
Kobajashi Togo IsamuAffiliation unknown2
Tamrin TamrinAffiliation unknown2
Arief WildanAffiliation unknown2
Hermawan IstiadiAffiliation unknown2
Fifin Luthfia RahmiAffiliation unknown2
Riski PrihatningtiasAffiliation unknown2
Barolym Tri PamungkasAffiliation unknown2
Lucky Dita AgustiansyahAffiliation unknown2
Fajar HidayantoAffiliation unknown2
Ayu SafitriUniversitas Halu Oleo2
Rimba HamidUniversitas Halu Oleo1
Amiruddin BAffiliation unknown1
La Ode MuharamAffiliation unknown1
Nuraini NurainiAffiliation unknown1
Yayah RukoyahAffiliation unknown1
Siti Hijrotul HopiahAffiliation unknown1
Lia NurkhalipahAffiliation unknown1
Syaw NurbillahAffiliation unknown1
Edwin PermanaAffiliation unknown1
Dhian Eka WijayaAffiliation unknown1
Martina Asti RahayuAffiliation unknown1
Moh NabawiAffiliation unknown1
Afrimanisa AfrimanisaAffiliation unknown1
Boima SitumeangAffiliation unknown1
Muhammad Mutfi Amin ShidqiAffiliation unknown1
Khairani FitriAffiliation unknown1
Tetty Noverita KhairaniAffiliation unknown1
Muhammad Amin NasutionAffiliation unknown1
Muhammad Fauzan LubisAffiliation unknown1
Jashima UkhtiaAffiliation unknown1
Asysyifa RianaAffiliation unknown1
Yuliati WidiastutiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://jurnal.ar-raniry.ac.id/index.php/biotik/oai, first harvested 6 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">IN VITRO PHARMACOLOGICAL ACTIVITY TEST OF TELANG FLOWER KOMBUCHA AS ANTIBACTERIAL Vibrio Cholerae AND Shigella dysenteriae THROUGH FERMENTATION BIOTECHNOLOGY METHOD</dc:title>
	<dc:creator xml:lang="en">Somantri, Ucu Wandi</dc:creator>
	<dc:creator xml:lang="en">Fadillah, M Fariz</dc:creator>
	<dc:creator xml:lang="en">Rezaldi, Firman</dc:creator>
	<dc:creator xml:lang="en">Pruschia, Isti Dwi</dc:creator>
	<dc:creator xml:lang="en">Margarisa, Dwiyarina</dc:creator>
	<dc:creator xml:lang="en">Maharani, Maharani</dc:creator>
	<dc:subject xml:lang="en">Kombucha</dc:subject>
	<dc:subject xml:lang="en">Telang Flower</dc:subject>
	<dc:subject xml:lang="en">Vibrio cholerae</dc:subject>
	<dc:subject xml:lang="en">Shigella dysenteriae</dc:subject>
	<dc:description xml:lang="en">Diarrhea that occurs in the digestive tract is a big problem for human intestinal health. This can be caused by the activity of pathogenic bacteria in the form of Vibrio cholera and Shigella dysinteriae. In this study, kombucha has been shown to have pharmacological activity in vitro in inhibiting the growth of Vibrio cholera and Shigella dysinteriae bacteria at all sugar concentrations. The purpose of this study was to determine the in vitro pharmacological activity of the butterfly pea flower kombucha in inhibiting the growth of the two test bacteria consisting of a sugar concentration of 20%, 30% and 40%. The method for testing the inhibition of both bacterial growth tests is disc diffusion. One way ANOVA and post hoc analysis are one of the quantitative test methods used in this study of the average diameter of the inhibition zone of teal flower kombucha from various sugar concentrations. The results of this study have proven based on a one-way ANOVA with each P value&amp;gt; 0.05 and then continued through post hoc analysis concluded that the telang flower kombucha at a concentration of 40% is the best treatment in inhibiting the growth of both test bacteria where the concentration is significantly different from sugar concentration 20% and 30%.</dc:description>
	<dc:publisher xml:lang="en">Universitas Islam Negeri Ar-Raniry</dc:publisher>
	<dc:date>2025-09-23</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:format>application/vnd.openxmlformats-officedocument.wordprocessingml.document</dc:format>
	<dc:identifier>https://jurnal.ar-raniry.ac.id/index.php/biotik/article/view/17427</dc:identifier>
	<dc:identifier>10.22373/biotik.v11i2.17427</dc:identifier>
	<dc:source xml:lang="en">BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan; Vol. 11 No. 2 (2023): JURNAL BIOTIK; 130-146</dc:source>
	<dc:source xml:lang="id">Biotik; Vol 11 No 2 (2023): JURNAL BIOTIK; 130-146</dc:source>
	<dc:source>2549-1768</dc:source>
	<dc:source>2337-9812</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://jurnal.ar-raniry.ac.id/index.php/biotik/article/view/17427/pdf</dc:relation>
	<dc:relation>https://jurnal.ar-raniry.ac.id/index.php/biotik/article/view/17427/11343</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2023 firman rezaldi</dc:rights>
	<dc:rights xml:lang="en">http://creativecommons.org/licenses/by-sa/4.0</dc:rights>
</oai_dc:dc>