Analisis Resiko Kejadian Akut Rekuren Demam Tifoid dan Hubungannya dengan Kadar Protein Nucleotide Binding Oligomerization Domain 2 (NOD2)

Wahyuni, Sri; Hatta, Mochammad; Hamid, Firdaus; Natzir, Rosdiana; Ahmad, Ahyar; Bahar, Burhanuddin; Junita, Ade Rifka; Dwiyanti, Ressy; Purnamasari, Nur Indah; Primaguna, Muhammad Reza; Sabir, Muhammad

doi:10.70561/jal.v12i2.17585

Jurnal

Analisis Resiko Kejadian Akut Rekuren Demam Tifoid dan Hubungannya dengan Kadar Protein Nucleotide Binding Oligomerization Domain 2 (NOD2)

Jurnal Ilmu Alam dan Lingkungan · Vol. 12 No. 2 (2021)

DOI: 10.70561/jal.v12i2.17585
ISSN: 2549-8819, 2086-4604
Published: 2021-08-23
Publisher: Universitas Hasanuddin
Language: en

Abstract

Typhoid fever is an infectious disease caused by Salmonella typhi bacteria and is endemic. The NOD2 gene is one of the host susceptibility genes in people with typhoid fever. NOD2 acts as an intracellular receptor that binds to the muramyl dipeptide ligand derived from bacterial peptidoglycan. The purpose of this study was to determine the levels of NOD2 protein in Acute Recurrent of Typhoid Fever (ARTF), typhoid fever (TF) patients, and healthy people (HP). Enzyme-linked Immunosorbent Assay (ELISA) was used to analyze NOD2 levels. The data analysis used was the student t-test. A significant difference of NOD2 level was found between the ARTF and TF group compared HP group (p

Collaboration network of the authors

40 authors · 143 co-authorship links · showing the 40 most connected

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Universitas Halu Oleo
Affiliation unknown

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Co-author	Organisation	Joint articles
Muhammad Syukri Sadimantara	Universitas Halu Oleo	11
SRI REJEKI	Universitas Halu Oleo	10
RH Fitri Faradilla	Affiliation unknown	10
Ansharullah Ansharullah	Universitas Halu Oleo	8
Andi Khaeruni	Universitas Halu Oleo	7
Hermanto Hermanto	Universitas Halu Oleo	6
Alfian Noor	Affiliation unknown	6
Asnani Asnani	Affiliation unknown	5
Nurhaedar Jafar	Affiliation unknown	5
LA KARIMUNA	Universitas Halu Oleo	4
Hasnah Natsir	Affiliation unknown	4
Juminten Saimin	Affiliation unknown	3
Tamrin Tamrin	Universitas Halu Oleo	3
Citrakesumasari .	Affiliation unknown	3
Muhammad Lukman	Affiliation unknown	3
Rakhmad Armus	Affiliation unknown	3
Waode Sitti Asfiah Udu	Affiliation unknown	2
Sufiah Asri Mulyawati	Affiliation unknown	2
Yenti Purnamasari	Affiliation unknown	2
Nur Asyik	Universitas Halu Oleo	2
Sarinah Sarinah	Affiliation unknown	2
Veni Hadju	Affiliation unknown	2
Safrullah Amir	Affiliation unknown	2
Muawanah Muawanah	Affiliation unknown	2
Seniwati Dali	Affiliation unknown	2
Hanapi Usman	Affiliation unknown	2
Muh. Nasrum Massi	Affiliation unknown	2
Mashuni Mashuni	Affiliation unknown	2
Rosana Agus	Affiliation unknown	2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/jai2/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.

Original metadata (oai_dc)

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	<dc:title xml:lang="en">Analisis Resiko Kejadian Akut Rekuren Demam Tifoid dan Hubungannya dengan Kadar Protein Nucleotide Binding Oligomerization Domain 2 (NOD2)</dc:title>
	<dc:creator xml:lang="en">Wahyuni, Sri</dc:creator>
	<dc:creator xml:lang="en">Hatta, Mochammad </dc:creator>
	<dc:creator xml:lang="en">Hamid, Firdaus </dc:creator>
	<dc:creator xml:lang="en">Natzir, Rosdiana </dc:creator>
	<dc:creator xml:lang="en">Ahmad, Ahyar </dc:creator>
	<dc:creator xml:lang="en">Bahar, Burhanuddin </dc:creator>
	<dc:creator xml:lang="en">Junita, Ade Rifka </dc:creator>
	<dc:creator xml:lang="en">Dwiyanti, Ressy </dc:creator>
	<dc:creator xml:lang="en">Purnamasari, Nur Indah </dc:creator>
	<dc:creator xml:lang="en">Primaguna, Muhammad Reza </dc:creator>
	<dc:creator xml:lang="en">Sabir, Muhammad </dc:creator>
	<dc:description xml:lang="en">Typhoid fever is an infectious disease caused by Salmonella typhi bacteria and is endemic. The NOD2 gene is one of the host susceptibility genes in people with typhoid fever. NOD2 acts as an intracellular receptor that binds to the muramyl dipeptide ligand derived from bacterial peptidoglycan. The purpose of this study was to determine the levels of NOD2 protein in Acute Recurrent of Typhoid Fever (ARTF), typhoid fever (TF) patients, and healthy people (HP). Enzyme-linked Immunosorbent Assay (ELISA) was used to analyze NOD2 levels. The data analysis used was the student t-test. A significant difference of NOD2 level was found between the ARTF and TF group compared HP group (p</dc:description>
	<dc:publisher xml:lang="en">Universitas Hasanuddin</dc:publisher>
	<dc:date>2021-08-23</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/jai2/article/view/17585</dc:identifier>
	<dc:identifier>10.70561/jal.v12i2.17585</dc:identifier>
	<dc:source xml:lang="en">Jurnal Ilmu Alam dan Lingkungan; Vol. 12 No. 2 (2021): Jurnal Ilmu Alam dan Lingkungan</dc:source>
	<dc:source>2549-8819</dc:source>
	<dc:source>2086-4604</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/jai2/article/view/17585/7254</dc:relation>
</oai_dc:dc>